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| 英文名稱(chēng) | brusatol |
|---|---|
| 中文名稱(chēng) | 鴉膽子苦醇/鴉膽苦醇/(1R,2S,3S,3aS,3a1R,4R,6aR,7aR,11aS,11bR)-甲基 1,2,9-三羥基-8,11a-二甲基-4-((3-甲基丁-2-烯?；?氧基)-5,10-二氧代-2,3,3a,4,5,6a,7,7a,10,11,11a,11b-十二氫-1H-3,3a1-(環(huán)氧甲基)二苯并[de,g]苯并吡喃-3-羧酸酯 |
| CAS號(hào) | 14907-98-3 |
| 分子式 | C26H32O11 |
| 分子量 | 520.53 |
| 外觀 | 白色結(jié)晶性粉末 |
| 沸點(diǎn) | 724.3±60.0 °C | Condition: Press: 760 Torr |
| 酸度系數(shù)pKa | 8.81±0.70 | Condition: Most Acidic Temp: 25 °C |
WKQ-0001288
中文名稱(chēng)：鴉膽子苦醇
中文別名：鴉膽苦醇；(1R,2S,3S,3aS,3a1R,4R,6aR,7aR,11aS,11bR)-甲基 1,2,9-三羥基-8,11a-二甲基-4-((3-甲基丁-2-烯酰基)氧基)-5,10-二氧代-2,3,3a,4,5,6a,7,7a,10,11,11a,11b-十二氫-1H-3,3a1-(環(huán)氧甲基)二苯并[de,g]苯并吡喃-3-羧酸酯
英文名稱(chēng)：brusatol
英文別名：2H-3,11cβ-(Epoxymethano)phenanthro[10,1-bc]pyran-3α(3aβH)-carboxylic acid, 1,4,5,6aβ,7,7aα,10,11,11a,11bα-decahydro-1β,2α,4β,9-tetrahydroxy-8,11aβ-dimethyl-5,10-dioxo-, methyl ester, 4-(3-methylcrotonate) (8CI);Picras-3-en-21-oic acid, 13,20-epoxy-3,11,12-trihydroxy-15-[(3-methyl-1-oxo-2-butenyl)oxy]-2,16-dioxo-, methyl ester, (11β,12α,15β)- (9CI);Crotonic acid, 3-methyl-, 4-ester with methyl 1,4,5,6aβ,7,7aα,10,11,11a,11bα-decahydro-1β,2α,4β,9-tetrahydroxy-8,11aβ-dimethyl-5,10-dioxo-2H-3,11cβ-(epoxymethano)phenanthro[10,1-bc]pyran-3α(3aβH)-carboxylate (8CI);(+)-Brusatol;Brusatol;NSC 172924;Yatansin;
分子式：C26H32O11
分子量：520.53
CAS號(hào)：14907-98-3
純度：HPLC≥98%
沸點(diǎn)：724.3±60.0 °C | Condition: Press: 760 Torr
密度：1.46±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
酸系度數(shù)：8.81±0.70 | Condition: Most Acidic Temp: 25 °C
儲(chǔ)存條件：-20℃，干燥、避光、密封
規(guī)格：5mg10mg20mg50mg100mg500mg1g2g等應(yīng)客戶(hù)需求包裝
供應(yīng)單位：四川省維克奇生物科技有限公司
供應(yīng)電話：028-81700200/4008005713
四川省維克奇生物科技有限公司生產(chǎn)中藥類(lèi)標(biāo)準(zhǔn)品和天然植物有效單體，主打中藥對(duì)照品/標(biāo)準(zhǔn)品/天然植物有效單體，化學(xué)合成，抗生素三大板塊。公司推出丹參系列、龍膽系列、蟲(chóng)草系列等，敬請(qǐng)關(guān)注！ 新批次有現(xiàn)貨，歡迎咨詢(xún)。
| Brusatol has therapeutic efficacy in non-small cell lung cancer by targeting Skp1 to inhibit cancer growth and metastasis | ||
| 來(lái)源：SCI：PHARMACOLOGICAL RESEARCH | 作者：Shangping Xing | 備注：影響因子：7.658 |
| 引用描述 | ||
Brusatol was purchased from Weikeqi Biotech (Sichuan, China) with the purity of > 98%. Cycloheximide (CHX), biotin, MG-132, cisplatin and SZL P1-41 were purchased from MedChemExpress (NJ, USA). Polyethylene glycol 300 (PEG300) and tween 80 were purchased from Macklin (Shanghai, China). | ||
